Platelet Acetyl-CoA Carboxylase Phosphorylation
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چکیده
منابع مشابه
Plant acetyl-CoA carboxylase.
medium containing [” Plphosphate, the distribution of 32P-labelled acetyl-CoA carboxylase in the fractions can be investigated and it has been found that a greater proportion of the phosphorylated enzyme is present in the polymeric form after exposure of the intact tissue to insulin. Present studies are concerned with investigating whether this polymeric active form is phosphorylated to a great...
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Acetyl CoA carboxylase was purified from liver of fasted-refed rats to near homogeneity, based on electrophoretic analysis and biotin content. These preparations contained an endogenous protein kinase that catalyzed the transfer of radioactive phosphate from [gamma-32P]ATP to acetyl CoA carboxylase, accompanied by a decrease in acetyl CoA carboxylase activity. Phosphate incorporated into acetyl...
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Acetyl-CoA carboxylase [acetyl-CoA:carbon-dioxide ligase (ADP-forming), EC 6.4.1.2] is activated by physiological concentrations of CoA. The CoA concentration dependency of this activation is sigmoidal; below 60 microM there is little or no activation, but the activation observed between 60 and 120 microM indicates that small changes in the concentration of CoA can cause significant changes in ...
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23 Holloway, P. J., Wong, W. W. C., Partridge, H. J., Seaman, D. and Perry, R. B. (1992) Pestic. Sci. 34, 109-118 24 Silcox, D. and Holloway, P. J. (1989) in Adjuvants and Agrochemicals (Chow, P. N. P., Grant, C. A,, Hinshalwood, A. M. and Simundsson, E., eds.), pp. 115-128, CRC Press Inc., Boca Raton, FL 25 Coret, J., Garnbonnet, B., Brabet, F. and Charnel, A. R. (1993) Pestic. Sci. 38, 201-20...
متن کاملRegulation of mammalian acetyl-CoA carboxylase.
Acetyl-CoA carboxylase (ACC) plays a critical role in the regulation of fatty acid metabolism and its two isoforms, ACCalpha and ACCbeta, appear to have distinct functions in the control of fatty acid synthesis and fatty acid oxidation, respectively. They are regulated by similar short-term mechanisms of allosteric activation by citrate, and reversible phosphorylation and inactivation, and ther...
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ژورنال
عنوان ژورنال: JACC: Basic to Translational Science
سال: 2019
ISSN: 2452-302X
DOI: 10.1016/j.jacbts.2019.04.005